Effective, instant, proven methods. Once you minimize the inflow of toxins or triggers, you can take steps to mobilize toxins and enhance toxic outflow. Activated charcoal is a great detoxifying agent that may be helpful for lowering allergy-induced inflammation. Omega-3 fats improve the bodys ability to produce adenosine depleted oxygen (DAO). Did Living in Italy Start My Histamine Troubles? How does this affect effectively using the HistAssist when one with MCAS needs to avoid high histamine foods and sources? Common symptoms are: Abdominal cramps Abnormal menstrual cycle Anxiety Arrhythmia, or accelerated heart rate Difficulty falling asleep Difficulty regulating body temperature Fatigue Flushing This medication has not been linked to any other side effects. So sick of this merry go round. Chronic stress can kick your immune system into overdrive and allow troublemaking microbes to flourish. I have even seen a homemakers category. Brain histamine increases alertness and focus and decreases pain and the desire to eat; these changes are part of the fight or flight response and prepare the body to respond to danger [].. , NOW GET MY FULL HEALING GUIDE MASTERCLASS. I have been under self care because I lost my insurance. Prepare the water by bringing 1 quart to a rapid boil. I am not ready to try those yet. I was diagnosed in Boston with MCAS in 2015. Some patients who experience restless sleep, hives, sinus congestion, muscle twitches, heart pounding, heart palpitations, particularly strong hypnic jerks (those muscle contractions you get when you are falling asleep), or full-blown insomnia at night can get significant relief when they take activated charcoal. Low dose naltrexone can decrease inflammatory cytokine production which may aid in improving mood and weight loss. Activated charcoal has been shown to effectively absorb pesticides, herbicides, mold toxins, endotoxins and more. I thought it was supposed to help me sleep so Im glad to see your thought about insomnia related to LDN. Are You Concerned About Mast Cell Activation Syndrome? I am uninsured, so its nearly impossible to see an allergist, etc. I knew it was a matter of time that functional medicine mapped out the pathways. Your body cannot make enough DAO enzymes to break down histamine, so the symptoms of a gut infection must be accompanied by symptoms of a lack of health. Powerup to unlock perks for r/HistamineIntolerance Im dealing with chronic urticaria,stomach aches, lung flare ups, low blood pressure and more. This is pretty low-tech, but as someone who gets ocular migraines from certain types of light and changes in light, Ive found that avoidance helps me, so maybe this would help with the distraction issue, too. This was not a result I expected but maybe I do have MCAS after all! I have always had IBS and fibro, and food intolerances from birth. Food compounds, besides histamine, are also converted to DAO enzymes in the body. Wine aged in oak barrels is a huge histamine trigger so you are actually best to avoid wine or ironically get a less expensive bottle that was not aged in oak. Natural antihistamines like stinging nettle, quercetin, butterbur, bromelain, and probiotics may also help to reduce the effects of histamine. Thank you. This has been happening gradually for the last 7 months. I am so happy to get this information from you! These foods may help to reduce histamine levels in foods by breaking them down. I have sometimes severe histamine intolerance attacks, its under control most of the time but things that some sites say are OK (like coffee) can send me into a bad attack. Im down to chicken stock and boiled meat. I wonder if you have any experience using LDI (low dose immunotherapy) for patients whose MCAS was triggered by Bacterial LPS from dental cavitations. Thank you for sharing your journey. I also have had burning in my vaginal area and pain. warmly Thank you for bringing awareness to the sensitivity that MCAS patients experience. Pour the herb-infused water and the warm water into a foot basin (or turkey roasting pan). It cuts into itevery time. (A big claim I know, but this is what we are aiming for, starting NOW). I have a telephone appointment scheduled with one of the dietitians that you work with to help figure out a plan to add foods so that my weight loss stops. The Foundation Center Library, now merged with Candid.org, was founded in the 1950s, is the go-to source for nonprofits, their books are in many mainstream and University libraries. The most common symptoms of histamine intolerance include: 1. Nor should you ever delay seeking medical advice or treatment due to the information contained on this Website. When the water has boiled, remove from heat, add the fresh herbs (if using, and let stand, covered, for 10 minutes to steep. Increase issues have cause nerve firing and adrenal stress with cognitive challenges. Innate immunity includes things like your cough reflex, your skin, stomach acid, or mucus as well as the release of proinflammatory signaling molecules that sound the initial alarm to activate the rest of your immune system. Best to you in healing . They worship Trump. .best. Tumeric root (but not extract) is high oxalate Vitamin C metabolic end products include high amount of oxalic acid Oxalate can grow on molds/ fungi And on and on. Quercetin, in addition to healing the gut and promoting a healthy immune system, is an important component of gut health. I watch my diet super closeas well as any chemicals in my environment. If you need some help finding ways to manage and reduce stress, check out my article, Be Happier & Less Anxious with 7 Minutes a Day, 9. Im an RN and have seen many patients with this issue in varying levels of severity. After all of my research I decided that I had nothing to lose by trying LDN and asked my local gastroenterologist who agreed to my request to try LDN. Mar 25, 2023. Diamine oxidase (DAO) is the main enzyme responsible for degrading histamine. I cant find a Dr to help me I have 4 safe foods. Members. We are not alone, and it is not in our head. Evidently most inhalers have some form of salicylic acid in them (asprin) and will make asthma symptoms worse in a handful of people. Im so weak from being unable to eat I cant even stand. Thank you all. When searching, note the grantors funding history, their philosophy, and weave this into your grant proposal. Honestly, I dont know if it is working or not. anxiety. Thanks so much for sharing. Im hoping to get much more but improvement when I heal from my long Lyme treatment. Vitamin B12: Could You Have an Undetected Deficiency in This Important Vitamin? Thanks for your many posts on MCAS. Hi. I tolerate aspirin so they have me on 81 mg twice a day although I know it can be a trigger for some. My diet hasnt changed, no new environmental factors, etc. http://www.candid.org this is not a grant making entity, but instead is a library specializing in nothing but grants of all kinds. Right after breastfeeding my symptoms came back and worse. Hi Dr. Jill, This information has provided hope for recovery from illness persisting from my covid-19 infection in March of 2020. 2023 Jill Carnahan. I suggest trying Dr. Theoharides or Dr. Afrin I tried LDN also. There are a variety of anti-inflammatory and natural antihistamine foods that can be added to your diet. Thank you for the wonderful post, as always. Ive read the entire LDN book and many publications etc (I am a retired dentist and biochemistry major so have some medical knowledge). Still irritated but with no pain. This is why many people with allergies report experiencing morning attacks or sleep disruptions. Because triggers for MCAS can be wide-ranging and unique to each individual, it can be helpful to keep a daily journal of any emotions, events, or activities that triggers your symptoms. Keep it up! warmly As an opiate antagonist, naltrexone competes with opioid drugs for real estate on opiate and endorphin receptors. Ps: I forgot to mention Ive tried histamines types 1 and 2, ketotifen and cromolyn but nothing has worked for the urticaria. Well, Im not able to take ANY of those supplements, and am down to eating one food, again. I was so sick with attacks of tachycardia, near syncope, shortness of breath , severe abdominal bloating and bright red hot flushing over face,neck and chest. Thank you for all of the helpful information on MCAS. I dive deeper into histamine-containing foods in my article, Mast Cell Activation Syndrome (MCAS): When Histamine Goes Haywire, The Histamine and Tyramine Restricted Diet. Mast cells participate in the direct defense against invading pathogens in a few ways:10,11,12. Some say this is a mast cell disorder and other put it in its own category . I was a gymnastics coach. 112, Activated charcoal is often used in emergency management of poisoning to prevent toxins from being absorbed through the stomach into the bloodstream. Surely there must be a progression of medical events, and these in my humble patients experience and viewpoint, are often missed in mainstream medical testing. Now lets zoom in on exactly what happens once these PAMPs bind to your TLRs and how these specialized receptors help your body fight infections. She devoted her journalism skills to researching and writing about histamine. Mar 17, 2023. The weight will NOT stop piling on! Taking antihistamines at this point just doesnt relieve me. dr Jill. Heres the link to the NCBI article re: piecemeal Degranulation. Eat healthy monounsaturated fats and saturated fat instead. Dr Jill I have been given Ldn by environmental doctor buscher in Redmond Washington but I havent used it yet Im nervous too.. I see the formula uses Pineapple. Histamine is part of the body's alarm system. Chronic stress can kick your immune system into overdrive and allow troublemaking microbes to flourish. I have great success with famotidine (Pepcid) taken at bedtime, and with ketotifen (Raditor eye drops). So if your circadian rhythm gets thrown off with irregular sleep patterns or poor sleep quality, mast cells can lose their own rhythmicity. Be persistent and patient, knock on several doors. A handful of mint leaves + 4 rosemary sprigs. In other words, theyre amazed I feel as good as I do! I currently take Claritin 3 times a day, Zantac twice a day, singulair once a day, ketotifen 2 times a day (which I get from Canada drugs online). I think this is extremely unkind to patients, and is medically irresponsible. Antihistamines make me agitated and depressed so I am looking into a more herbal/holistic approach. Peggy. It is a very difficult road to navigate medically, especially from a wholistic viewpoint. A few well-known, natural compounds that exhibit mast cell stabilizing activities include: But the truth is, having to take a conglomeration of antihistamines and mast cell stabilizers (on top of potential DAO supplements) can get expensive and overwhelming. If you want to get histamine out of your system faster, try eating Vitamin C-rich foods like tropical fruits, citrus fruits, broccoli, cauliflower, and berries. warmly I even started out at 0.5, and went down to 0.25mg, but after 2.5 months I had to quit. Now lets explore how your toll-like receptors can become overactivated and subsequently trigger your mast cells to become overactive resulting in a condition known as. Recently I was told about hydrogen therapy and after second treatment ( 20 minutes inhaled gas) three days apart stormed. Avoiding foods that are high in histamines, such as aged cheeses, fermented foods, and processed meats, can help reduce the histamine levels in your body. Today were going to explore exactly why vitamin B12 is so important, the consequences of being deficient in this nutrient, the problem with conventional B12 testing, and most importantly what steps you can take if youre concerned about a deficiency. Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/12847495. Eating plenty of quality protein and healthy fats paired with slow-digesting carbs will help fuel beneficial bacteria while starving out harmful bacteria. It provides more alternatives to the sometimes unsuccessful treatment protocols. Consider, also, oxalate content in herbs and supplements. Bringing this to light in the functional medicine arena is a exciting. Histamine intolerance is a type of food intolerance that affects people. Im not a big drinker at all but like to occasionally have a glass of red wine which i havent been able to do in over 1.5 years. DAO supplements increase the DAO levels in the digestive tract reducing the level of histamine entering the bloodstream and floating around in your body which can provide some relief from the symptoms associated with histamine overload. I had the great pleasure of getting to hear Dr. Theoharides in Seattle at The Forum for Integrative Medicine. Histamine intolerance means that you have too much histamine, usually because you can't break it down properly, which can result in various symptoms and health issues, including allergies, chronic congestion, chronic runny nose, headaches and migraines, hives, eczema, psoriasis, fatigue, anxiety, diarrhea, tachycardia, low blood pressure, Can you point me to the type of labwork I would need? Activated Charcoal: cleans, polishes and whitens teeth and freshens breath (black formula). It all comes down to specific receptors known as, You see, each species or strain of pathogen has its own unique structure or molecular pattern known as, As these pathogens make their way throughout your body, they inevitably bump into your cells including mast cells, Your mast cells (and other immune cells) contain a variety of receptors capable of recognizing specific pathogen patterns including toll-like receptors, When pathogens bump into mast cells TLRs, these receptor sites essentially detect and latch onto the microbes pathogen-associated molecular patterns, Once a PAMP is bound to your mast cells toll-like receptor, your cell releases molecules that launch your immune system into action and activate other immune cells. 112(1), 175-179. Hi Lisa Histamine intolerance symptoms can include rashes, hives, itching, headache, migraine, anxiety, depression, fatigue, insomnia, vertigo and GI disorders. So if your circadian rhythm gets thrown off with irregular sleep patterns or poor sleep quality, mast cells can lose their own rhythmicity. These symptoms resolved in 10 weeks, followed by a sudden onset of gastroparesis and severe reflux (had to get IV fluids often for 7 weeks and no prior history). That's where functional medicine comes in. Does what I describe sound like MCAS or just histamine intolerance or neither? Today were going to explore exactly how your immune system works, what mast cell activation syndrome is, what sets these misbehaving mast cells off in the first place, and most importantly explore some tried and true along with some brand new treatment options when it comes to addressing this complex condition. Dr Jill. Hi Dee She did extensive immune testing at that time. Online. I do castor oil now and all my supps to stabalize my mast cells. Im plateauing with my recovery and am hoping to find solutions to get me back to normal. Furthermore, starting an elimination diet that only entails eating and drinking substances with low levels of histamine can help flush it out of the body. I do want to comment on your website. Your email address will not be published. I also attribute this in part to the LDN. The Low-Histamine Food List. Activated charcoal is an effective natural remedy for histamine intolerance. It can take several months for Boards to review applications and select their winning applicants. Activated charcoal traps chemicals in the pores of activated charcoal. I have to avoid heat, sun, cold (I get cold urticaria really bad) and anything with preservatives in it. I cant take most DAO boosters due to the fact they are developed from porcine. Lets dive in. This was not an issue before, and I am attributing it to an event which caused my already-existing MCAS to flare even more than before. The long term exposure to multiple mycotoxins can deplete and suppress ones immune system, energy ATP production, etc. Mold is a Major Trigger of Mast Cell Activation Syndrome. I currently am taking several supplements but no other drugs besides the LDN. It started with itching all over my body and then the hives appeared. Even with all the treatment methods outlined above, some people may continue to struggle with MCAS symptoms. Dear Dr Jill et al, for those needing medical coverage but can not afford it, here is a source that may possibly fill in some of the gaps. Thank you, Too much histamine can cause a variety of symptoms and, as a result, diet factors. I appreciate 9 methods you share. Activated charcoal is made by heating the charcoal in the presence of a gas. Histamine, a naturally occurring chemical, causes severe allergy symptoms. Two major environmental triggers of MCAS include mold and an elevated overall toxic burden which you can read about here: If youre struggling with MCAS, its absolutely essential to reduce the bodys microbial and toxic burden. I also have Lyme and Babesia. In addition to food, there are many other causes of symptoms such as medication, stress and especially poor gut health so any one of these could still be causing your symptoms. This changes its structure. Digestive symptoms, such as diarrhea. But How Do I Know if I Have Histamine Intolerance? My biggest symptoms are bladder and urinary pain. When the trigger is removed, inflammation subsides and your mast cells return to their baseline standing guard and waiting for the next threat. I was diagnosed with MCAS last year and treated it mostly with diet and antihistamines. im dealing with the same stuff you are. Be sure, in your grant proposal, while outlining need to also be a feather in their cap. Just a few examples of specific PAMPs that TLRs can identify and bind to include:6,7,8,9. Hi, I Have Lyme, Bartonella and other co infecfions as well as MCAS. * Reducing stored oxalate in tissues can take years. I really believe that Dr. Theoharides NeuroProtek product is helping me (only started in October). Dee, I couldnt agree with you more. Mast Cell Activation Syndrome Histamine Intolerance Salicylate Intolerance Subclinical Porphyria You'll notice that Mast Cell Activation Syndrome and Histamine Intolerance are in the list above. I had a ct angio in June w contrast and seem much more reactive since. Producing more DAO can be accomplished by consuming the building blocks required for producing it. My throat feels like it will close when I eat beans. We all now may possess longer hair and achieve more options. But add whatever protein you like. The most effective first line of help seems to be Quercetin and Vitamin C and stopping the high histimine foods. In the meantime, I will try a low-histamine diet for two weeks but seeing as the anti-histamines did not give me any improvement, I doubt it will work for me either. I am taking Singulair, adviar, reactine 20mg daily as well as prevacid. just suggestions to research. Eating whole foods rich in nutrients and avoiding processed foods will help to support DAO naturally. Join Dr. Jills' health community today and receive health tips, recipes and recommended products for a healthier you! I have increased RF, eosinophils, colonoscopy showed increased eosinophils, some other inflammatory markers increased. It helps to reduce the absorption of histamine in the body, which can significantly reduce symptoms associated with histamine intolerance. Add plenty of DAO-boosting olive oil and fresh antihistamine herbs like parsley or cilantro. Hi Kelly Activated charcoal, when used in conjunction with water, reduces the absorption of substances in the stomach and intestines. Our youngest son, Trey is graduating from a masters of Pharmacology program in a few weeks and will begin LSU medical school in July. Furthermore, the study concluded that diphenhydramine was safe and well-tolerated in subjects with no major side effects. If I push through the reactions, it does get better after a week or so, but I get pretty much back to where I started. Now Im headed to the supplement drawer for Quercetin, and Vit C including slow release Vit C. I suspect that will help. All Rights Reserved | Site by Yakadanda |FAQS | Disclaimer | Financial Policy | Privacy Policy | Terms and Conditions. I just had a reaction to high dose B5 that lasted a week long! Mix together the contents of 2 pills of charcoal, 2 drops of moringa oil, 1 teaspoon of cucumber hydrosol in a ceramic bowl. As is now increasingly well known, Long COVID (LC) includes a wide array of symptoms and deficits and has been found in anywhere from 5-50% of individuals after recovering from COVID-19. Feeling hopeless . and may not be reproduced, resold, distributed, transmitted, displayed, published or broadcast except for the customer's personal use, without the prior written permission of Histamine, LLC dba Healing Histamin3, Numerous studies have documented the role of stress hormones on mast cell activation and histamine release. Some wild caught salmon, if tolerated, is a great source of protein paired with anti-inflammatory omega-3 fatty acids. It was the most miserable time of my life. Im unable to eat anything. should I go ahead and transition off of the omeprazole? I have taken LDN in the past for CFS and this article brought me to the following question, would you utilize LDN and Ketotifen simultaneously? Activated charcoal forms non-IgE binding complexes with peanut proteins. In fact, I am off low histamine diet, off H1 H2 antihistamines and Cromolyn Sodium. Yes, you read that right, mast cells do indeed have a circadian rhythm meaning your mast cells are more reactive during certain times of the day and less reactive during others. I forgot to mention that slow and steady mycotoxin detox was part of my treatment also. Hoping for more answers. Maybe the hormones play a role in this? This is not advice, it is intended for information and discussion only., Thankfully, charcoal tablets are now a last resort for me, but once upon a time, I relied on them regularly. It is imperative to LOWER the amount of oxalate in the diet SLOWLY. Strain into a 1 quart container and discard (compost) herbs. Its the only thing making me anke to eat everything i want get jo from bed . I was diagnosed with MCAS a year ago, and have been dealing with CIRS, EDS, Lipidema, Lyme and Mold illness as well. High levels of histamine (sometimes described as Histamine Intolerance) is a very common underlying cause of insomnia that is rarely treated or tested for. Or can you recommend some one closer? Wish LDN would have helped. Thank you, Jim! Diagnosed with interstitial cystitis, hashimotos and alopecia. if sensitive to sulphur foods Sensitivity to sulphur-rich foods (tied to hydrogen sulfide gas in the gut) can take time to resolve Lowering oxalates while healing microbiome will help folks increase intake of beneficial sulphur-rich foods (slowly, over time) Eat organic! a unique patented formula with 20,000 Histamine Degrading Units (HDUs) per serving to replenish and restore your DAO levels. It has really helped me with sleep but I have not yet seen help with the IC. So, sit back, relax, and learn about some of the best histamine-lowering ways to bring the spa experience to your home. Thankfully, charcoal tablets are now a last resort for me, but once upon a time, I relied on them regularly. Lymes test was negative. Thanks for your feedback, Jenny! This can make it difficult to pinpoint or diagnose. Studies have found that serum mast cell histamine levels were lower in the afternoon and highest at night. Preservatives are harmful to your health, so eat lots of fresh, non-preserved foods. Upon binding to PAMPs, your TLRs activate downstream signaling resulting in cascading reactions where mast cells mount an immune response. Working with some functional drs to trying to slow the isswie. Thats where DAO supplements come in. My symptoms started in college and have worsened over the past 7 years. Some ways to support the health of your gut include: If youre looking to soothe your mast cells and restore calm to your immune system, you simply cant afford to ignore your gut health. While it may not remove all pollutants, there are studies that show sweating is an effective and safe method for removal of toxic compounds that can accumulate within your body such as: To work up a sweat and boost your detoxification, aim for at least 30 minutes of moderate exercise every day or incorporate regular, The health of your gut and the composition of your gut microbiome play an intricate role in your immune system thanks to a channel known as the, . Theyre a mast cell stabilizer for the eyes. Some better options to focus on are natural sources of antihistamines like: These natural antihistamines can help soothe symptoms and naturally reduce histamine levels. Or make a colorful fruit salad with fresh mint or basil ribbons. (SLC26A ). Most holistic practitioners have a blindspot when it comes to oxalates (There is *so much more* to the picture than hyperoxaluria, kidney stones, and evaluation of OAT test ratios) . You should no longer have any symptoms after consuming low histamine for three to four weeks. They are always red with pterygium. Lyme and mold brought out my mcas. 4.4k. Hi Christina Healing Histamine is getting upgraded. As more immune cells make their way to the site of the threat, your mast cells continue to create and release a steady stream of signaling molecules reloading their weapons and stoking the cycle of inflammation.5. Mast cells participate in the direct defense against invading pathogens in a few ways: Mast cells are able to engulf or ingest pathogens to directly neutralize them. I have not been able to tolerate using OTC antihistamines (Zyrtec, Claritin, etc) so hoping this might help. Mold allergies and Mold biotoxins also known as mycotoxins can pose a serious risk factor for people who struggle with histamine intolerance/Mast Cell Activation Syndrome. In mast cell activation syndrome, or MCAS, chronic TLR activation creates hypersensitive mast cells that get stuck in overproduction mode setting off an inflammatory response that can spread throughout your body. I also suggest Low-dose naltrexone and maybe ketotifen for mast cell stabilization. tissue swelling. Histamine intolerance is exacerbated by poor gut health. Its the only relief Ive found. It is of great help to me in the treatment of my illness. As a general rule, you have to avoid hair products and treatments that contain chemicals like parabens, DEA and sulfates. I find that many things that work for other people.even Thought Field Therapy, if done too much, it makes things worse. Heart pounding or palpitations at night are also often written off as anxiety when they too can be the result of excess histamine. This helps patients feel less high from opioids or alcohol and reduces cravings. Worsening eczema, or a condition that causes itchy and flaky rashes. Rather, what relieves me of this feeling is to ingest a bigger amount of any trigger, where I feel a boost of the allergic reaction, and this is where taking antihistamines at this point effectively relieves me. Do you do patient video appointments? How to Naturally Boost Your Diamine Oxidase (DAO) Levels, Whats Lurking in Your Cleaning Products? Im an ICU nurse and I had to go out on disability because the attacks interfered with me being able to care for patients. Also want to have the HLA DR antibody tested that you mentioned in one of your podcast. You may try DNRS by Anne Hopper or desensitization therapy with a trained therapist. However, these symptoms were very correlated with my vaccine. I have been taking clonzapam every three days it seems to calm things a bit but dontlast and I heard they are bad for you.. Can you please help me I say momma randomly outloud and not on purpose.. Mucus lining all seems to go together like the taste in my mouth is causing yeast and symptoms in vaginal area nose is dry inside and I have been having a weird symptom in left eye blurry and like something is pulling in outer part of eyeball on left eye.. I cannot even take antihistimines without reaction. Dr. Jill. Sarah I am so sorry to hear about your suffering. My PCPs first thought was histamine reaction. I guess it is God and I to figure it out. I live in Kuna idaho..im very toxic. Also breathing issues, fatigue, joint/muscle pain, pelvic pain, hair loss and chronic diarrhea. An article published in the journal Nutrition Reviews claimed that activated charcoal was effective at reducing intestinal gas, bloating, and abdominal cramps, and one study found that it was far superior to placebo in reducing those symptoms. Consult the work of Dr. Stephanie Seneff,, Susan Owens, Donna Gates (Body Ecology) and Sally K. Norton (Toxic Superfoods) . since the testimonies are only a tiny bar on the right as you scroll down I will not likely change it but I do appreciate your feedback , Hi, Jenny. thank you. This branch of your immune system deploys specialized immune cells and proteins known as. Hi Jill! Hi Erica, how are you doing now? Dr said xolair would help but Im nervous about the side effects. I believe it has helped me in may ways. As HNMT (the other enzyme that nullifies histamine) activity takes place in the liver, a healthy liver is crucial for histamine intolerance. To treat histamine intolerance, a gluten-free diet should be avoided in addition to healing the gut. Not only do these oils have antihistamine properties, but they also have antiageing and skin beautifying benefits. I suspect that mast cell/histamine issues play a role because when I have taken Zyrtec daily for a over a year and it helps with the frequency issue. I have contended with MCAS, Lymes, Bartonella, SIBO, Lupus, POTS, Candida , Severe histine issues plus.

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